There is no recommendation to routinely screen for chlamydia among heterosexual males. But, screening sexually active adolescent and young adult men should be considered in clinical settings with a high prevalence of chlamydia (e.g., adolescent clinics, correctional facilities, and sexually transmitted disease clinics) or in populations with high burden of infection (e.g., gay, bisexual, and other men who have sex with men (MSM)).

Recommended Screening

The following screening tests should be performed at least annually for sexually active MSM, including those with HIV infection:

  • Test for urethral chlamydial infection in men who have had insertive intercourse during the preceding year, regardless of condom use (testing of the urine using nucleic acid amplification testing (NAAT) is the preferred approach).
  • Test for rectal chlamydial infection in men who have had receptive anal intercourse during the preceding year, regardless of condom use (NAAT of a rectal specimen is the preferred approach).
  • If at increased risk (e.g., are HIV-positive or if they or their sexual partners have multiple partners) these tests should be performed every 3-6 months.

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